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- For similar words and other spellings, see Cane (disambiguation).
Cain is the first son of Adam and Eve, according to the Bible Cain may also refer to:
Real people
- Dean Cain, an American actor
- Herb Cain, a professional Canadian ice hockey player
- James M. Cain, an American crime writer
- Liz Cain, Australian ice skater
- Matt Cain, a baseball pitcher
- Tim Cain, an american video game programmer
Fictional characters
- Cain, a murderous drug-dealer in the film RoboCop 2
- Commissar Ciaphas Cain, fictional character from the Warhammer 40,000 universe
- Cain Dingle, Emmerdale character
- Cain (fictional character), the decoy assassin in Robert Ludlum's The Bourne Identity
- Cain Nightroad is the main villain from the anime Trinity Blood
- Cain of Cain and Abel (comics), most notably seen in the Sandman series, is a fictional character from DC Comics based on the biblical Cain
- David Cain (comics), a fictional character from DC Comics and father of the current Batgirl
- Cain Marko, a fictional character from Marvel Comics known as the Juggernaut
- Cain, a fictional character from the anime Bleach
- Commander Cain, of the Battlestar Pegasus in Battlestar Galactica
- Deckard Cain, a character in the Diablo video game series.
- Helena Cain, Admiral in Battlestar Galactica
- Cogliostro, a supporting character in Todd McFarlane's Spawn comic series, is later revealed to be Cain.
- Wyatt Cain, a fictional character in the Sci-Fi channel miniseries Tin Man
Other
- The Mark of Cain, an Australian hard rock band
- Cain (play), a play by Lord Byron
- Cain (software), password cracking software
- CAIN or Conflict Archive on the Internet, a website documenting the Northern Irish 'Troubles'
- Cain (club), nightclub in Manhattan on 27th Street in Chelsea.

