All matter in the universe is composed of atoms. Atoms, in turn, are comprised of differing combinations of subatomic particles. The subatomic composition of an atom determines which element it is, and therefore what physical and chemical properties it...

Binding energy is the term used to specify the amount of energy necessary to hold components of a system together, usually in describing the interactions within constituents of molecular, atomic or nuclear systems. However, it can also be used in...

Binding energy is the mechanical energy required to disassemble a whole into separate parts. A bound system has a lower potential energy than its constituent parts; this is what keeps the system together. The usual convention is that this corresponds to...

ABSTRACT The second generation Mining Minima method yields binding affinities accurate to within 0.8 kcal/mol for the associations of α-, β-, and γ-cyclodextrin with benzene, resorcinol, flurbiprofen, naproxen, and nabumetone. These calculations require hours to a day on a commodity computer. The calculations...

ABSTRACT Glucose/galactose binding protein (GGBP) functions in two different larger systems of proteins used by enteric bacteria for molecular recognition and signaling. Here we report on the thermodynamics of conformational equilibrium distributions of GGBP. Three fluorescence components appear at zero glucose concentration and...

Every once in a while someone will ask me, “Why don’t you write about Rosanne Cash anymore? And hey, whatever happened with your marriage proposal to her?” It’s true that I was one of the first (or, anyway, one of the most effusive) to praise...

Every once in a while someone will ask me, “Why don’t you write about Rosanne Cash anymore? And hey, whatever happened with your marriage proposal to her?” It’s true that I was one of the first (or, anyway, one of the most effusive) to...